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CHAMPion   

Title

Cancer-induced Hypercoagulability as a marker of prognosis


Basic Trial Information

Phase Type Status Age Sponsor Protocol IDs Recruitment
II Observation Open 18 and over University of South Manchester Eudract No:
Isrctn No:
0

Purpose

Prospective clinical cohort study investigating durtion and significance of hypercoagulable response to surgery, correlated with tumour molecular phenotype and outcome. Pre ans post-operative plasma markers of clotting cascade activation, platelet activation, fibronolytic activity and activation of coagulation will be compared to tissue expression of equivalent markers, development of clinical VTE, tumour clinicopathological prognostic factors, and survival in patients undergoing elective abdominal and breast cancer surgery. Patients undergoing non-cancer surgery (matched for age, sex and type of surgery to the cancer patients) will provide baseline response to surgery.


Trial Lead Organisations

University of South Manchester


Trial Start Date

Trial Not Open


Trial Coordinator

Gemma Nanson


Trial Coordinator Email Address

g.simpson@liv.ac.uk


Trial Coordinator Contact No

0151 794 8974


Links  

http://public.ukcrn.org.uk/Search/StudyDetail.aspx?StudyID=8685