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  1. Nicholson JA, Greenhalf W, Jackson R, Cox TF, Butler JV, Hanna T, Harrison S, Grocock CJ, Halloran CM, Howes NR, Raraty MG, Ghaneh P, Johnstone M, Sarkar S, Smart HL, Evans JC, Aithal GP, Sutton R, Neoptolemos JP, Lombard MG. Incidence of post-ERCP pancreatitis from direct pancreatic juice collection in Hereditary Pancreatitis and Familial Pancreatic Cancer before and after the introduction of prophylactic pancreatic stents and rectal diclofenac. Pancreas. 2015; 44: 260-265.

 

  1. Thomas Hanna, Zainab Abdul-Rahman, William Greenhalf, Eithne Costello, John P. Neoptolemos. Pancreatic mass in a young CFTR carrier with a heterozygous p.R117H CFTR gene mutation and homozygous 7T. Pancreas. 2015; 44: 343-345.

 

  1. Athwal T, Huang W, Mukherjee R, Latawiec D, Chvanov M, Clarke R, Smith K, Campbell F, Merriman C, Criddle D, Sutton R, Neoptolemos J, Vlatkovic N.Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell death. Cell Death and Disease. 2014; 10; 5:e1165. doi: 10.1038/cddis.2014.120.

 

  1. Shaw VE, Lane B, Jenkinson C, Cox T, Greenhalf W, Halloran CM, Tang J, Sutton R, Neoptolemos JP, Costello E. Serum cytokine biomarker panels for discriminating Pancreatic Cancer from Benign Pancreatic Disease.  Molecular Cancer 2014 May 20;13(1):114. [Epub ahead of print].

 

  1. Jenkinson C, Elliott V, Menon U, Apostolidou S, Fourkala OE, Gentry-Maharaj A, Pereira SP, Jacobs I, Cox TF, Greenhalf W, Timms JF, Sutton R, Neoptolemos JP, Costello E. Evaluation in pre-diagnosis samples discounts ICAM-1 and TIMP-1 as biomarkers for earlier diagnosis of pancreatic cancer. J Proteomics. 2014 Oct 11. pii: S1874-3919(14)00464-3. doi: 10.1016/j.jprot.2014.10.001. [Epub ahead of print].

 

  1. Jenkinson C, Earl J, Ghaneh P, Halloran C, Carrato A, Greenhalf W, Neoptolemos J, Costello E. Biomarkers for early diagnosis of pancreatic cancer. Expert Rev Gastroenterol Hepatol. 2014; 6:1-11.

 

  1. Gomatos IP, Xiaodong X, Ghaneh P, Halloran C, Raraty M, Lane B, Sutton R, Neoptolemos JP.Prognostic markers in acute pancreatitis. Expert Rev Mol Diagn. 2014; 14(3):333-46.

 

  1. Campa D, Rizzato C, Capurso G, Giese N, Funel N, Greenhalf W, Soucek P, Gazouli M, Pezzilli R, Pasquali C, Talar-Wojnarowska R, Cantore M, Andriulli A, Scarpa A, Jamroziak K, Fave GD, Costello E, Khaw KT, Heller A, Key TJ, Theodoropoulos G, Malecka-Panas E, Mambrini A, Bambi F, Landi S, Pedrazzoli S, Bassi C, Pacetti P, Piepoli A, Tavano F, di Sebastiano P, Vodickova L, Basso D, Plebani M, Fogar P, Büchler MW, Bugert P, Vodicka P, Boggi U, Neoptolemos JP, Werner J, Canzian F. Genetic susceptibility to pancreatic cancer and its functional characterisation: The PANcreatic Disease ReseArch (PANDoRA) consortium.Dig Liver Dis. 2013; 45(2): 95-9.

 

  1. Campa D, Rizzato C, Bauer AS, Werner J, Capurso G, Costello E, Talar-Wojnarowska R, Jamroziak K, Pezzilli R, Gazouli M, Khaw KT, Key TJ, Bambi F, Mohelnikova-Duchonova B, Heller A, Landi S, Vodickova L, Theodoropoulos G, Bugert P, Vodicka P, Hoheisel JD, Delle Fave G, Neoptolemos JP, Soucek P, Büchler MW, Giese N, Canzian F. Lack of replication of seven pancreatic cancer susceptibility loci identified in two Asian populations. Cancer Epidemiology, Biomarkers & Prevention. 2013;22(2):320-3.

 

  1. Rizzato C, Campa D, Pezzilli R, Soucek P, Greenhalf W, Capurso G, Talar-Wojnarowska R, Heller A, Jamroziak K, Khaw KT, Key TJ, Bambi F, Landi S, Mohelnikova-Duchonova B, Vodickova L, Büchler MW, Bugert P, Vodicka P, Neoptolemos JP, Werner J, Hoheisel JD, Bauer AS, Giese N, Canzian F. ABO blood groups and pancreatic cancer risk and survival: Results from the PANcreatic Disease ReseArch (PANDoRA) consortium.Oncol Rep. 2013:29(4): 1637-44.

 

  1. Tonack S, Jenkinson C, Cox T, Elliott V, Jenkins RE, Kitteringham NR, Greenhalf W, Shaw V, Michalski CW, Friess H, Neoptolemos JP, Costello E. iTRAQ reveals candidate pancreatic cancer serum biomarkers: influence of obstructive jaundice on their performance.Br J Cancer. 2013; 108(9): 1846-53.

 

  1. Rachakonda PS, Bauer AS, Xie H, Campa D, Rizzato C, Canzian F, Beghelli S, Greenhalf W, Costello E, Schanne M, Heller A, Scarpa A, Neoptolemos JP, Werner J, Büchler M, Hoheisel JD, Hemminki K, Giese N, Kumar R. Somatic mutations in exocrine pancreatic tumors: association with patient survival. PLoS One. 2013; 8(4): e60870.

 

  1. Rizzato C, Campa D, Giese N, Werner J, Rachakonda PS, Kumar R, Schanné M, Greenhalf W, Costello E, Khaw KT, Key TJ, Siddiq A, Lorenzo-Bermejo J, Burwinkel B, Neoptolemos JP, Büchler MW, Hoheisel JD, Bauer A, Canzian F. Pancreatic cancer susceptibility loci and their role in survival.PLoS One. 2011; 6(11): e27921. Bauer AS, Keller A, Costello E, Greenhalf W, Bier M, Borries A, Beier M, Neoptolemos J, Büchler M, Werner J, Giese N, Hoheisel JD. Diagnosis of pancreatic ductal adenocarcinoma and chronic pancreatitis by measurement of microRNA abundance in blood and tissue. PLoS One2012; 7(4): e34151.

 

  1. Van Laethem JL, Verslype C, Iovanna JL, Michl P, Conroy T, Louvet C, Hammel P, Mitry E, Ducreux M, Maraculla T, Uhl W, Van Tienhoven G, Bachet JB, Maréchal R, Hendlisz A, Bali M, Demetter P, Ulrich F, Aust D, Luttges J, Peeters M, Mauer M, Roth A, NeoptolemosJP, Lutz M. New strategies and designs in pancreatic cancer research: consensus guidelines report from a European expert panel.Ann Oncol.2012; 23(3): 570-6.

 

  1. Whitcomb DC, Larusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L; Alzheimer's Disease Genetics Consortium, Albert MS, Albin RL, Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barnes LL, Beach TG, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carney RM, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, Cruchaga C, Decarli C, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Glass JD, Goate AM, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hamilton-Nelson KL, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, Kramer P, Kukull WA, Laferla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lin CF, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Naj AC, Olichney JM, Parisi JE, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Conwell D, Coté GA, Cotton PB, Disario J, Farrer LA, Forsmark CE, Johnstone M, Gardner TB, Gelrud A, Greenhalf W, Haines JL, Hartman DJ, Hawes RA, Lawrence C, Lewis M, Mayerle J, Mayeux R, Melhem NM, Money ME, Muniraj T, Papachristou GI, Pericak-Vance MA, Romagnuolo J, Schellenberg GD, Sherman S, Simon P, Singh VP, Slivka A, Stolz D, Sutton R, Weiss FU, Wilcox CM, Zarnescu NO, Wisniewski SR, O'Connell MR, Kienholz ML, Roeder K, Barmada MM, Yadav D, Devlin B. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet.2012 Dec;44(12):1349-54.

 

  1. Costello E, Greenhalf W, Neoptolemos JP. New biomarkers and targets in pancreatic cancer and their application to treatment. Nat Rev Gastroenterol Hepatol. 2012; 9(8):435-44.

 

  1. Tuveson D, Neoptolemos JP. Understanding metastasis in pancreatic cancer: a call for new clinical approaches.Cell 2012: 148(1-2): 21-3.

 

  1. Costello E and Neoptolemos JP. Pancreatic cancer in 2010: New insights for early intervention and detection. Nature Review Gastroenterology Hepatology. 2011; 8(2):71-3.
  2. Costello E, Neoptolemos JP. Enhancing the translation of cancer biomarkers.  British Journal of Surgery.2011; 98:1039-40.

 

  1. Rizzato C, Campa D, Giese N, Werner J, Rachakonda PS, Kumar R, Schanné M, Greenhalf W, Costello E, Khaw KT, Key TJ, Siddiq A, Lorenzo-Bermejo J, Burwinkel B, Neoptolemos JP, Büchler MW, Hoheisel JD, Bauer A, Canzian F. Pancreatic cancer susceptibility loci and their role in survival. PLoS One. 2011; 6(11): e27921.

 

  1. Schröder  C, Jacob A, Tonack S, Radon TP, Sill M, Zucknick M, Rüffer S, Costello E, Neoptolemos  JP, Crnogorac-Jurcevic T, Bauer A, Fellenberg K, Hoheisel JD.Dual-color proteomic profiling of complex samples with a microarray of 810 cancer-related antibodies. Journal of Molecular and Cellular Proteomics 2010; 9(6):1271-80.

 

  1. Slater EP, Langer P, Niemczyk E, Strauch K, Butler J, Habbe N, Neoptolemos J, Greenhalf W, Bartsch DK. PALB2 mutations in European familial pancreatic cancer families. Clin Genet. 2010; 78(5):490-4.

 

  1. Tonack S, Neoptolemos J, Costello E.  Principles and applications of proteomics in pancreatic cancer.  In: Neoptolemos JP, Urrutia R, Abbruzzese JL, Büchler MW (Eds).  Pancreatic Cancer. Springer, New York, 2010, 509-533.

 

  1. Greenhalf W, Neoptolemos J.  Genetic susceptibility and high risk groups for pancreatic cancer.  In: Neoptolemos JP, Urrutia R, Abbruzzese JL, Büchler MW (Eds).  Pancreatic Cancer. Springer, New York, 2010, 565-600.

 

  1. Greenhalf W, Neoptolemos J.  Inherited genetics of pancreatic cancer and secondary screening.  In: Neoptolemos JP, Urrutia R, Abbruzzese JL, Büchler MW (Eds).  Pancreatic Cancer. Springer, New York, 2010, 1203-1235.

 

  1. Grocock CJ, Rebours V, Delhaye M, Andren-Sandberg A, Weiss FU, Mountford R, Harcus M, Niemczyck E, Vitone L, Dodd S, Joergensen MT, Ammann RW, Schaffalitzky de Muckadell O, Butler JV, Burgess P, Kerr B, Charnley R, Sutton R, Raraty M, Deviere J, Whitcomb D, Neoptolemos J, Levy P, Lerch MM, Greenhalf W. The variable phenotype of the p.A16V mutation of cationic trypsinogen (PRSS1) in pancreatitis families. Gut.  2010;59(3):357-63.

 

 

  1. Tonack S, Neoptolemos JP, Costello E. Analysis of serum proteins by LC-MS/MS.Methods Mol Biol. 2010;658:281-91.

 

  1. Greenhalf W, Grocock C, Harcus M, Neoptolemos J. Screening of High-Risk Families for Pancreatic Cancer. Pancreatology. 2009; 9(3): 215-222.

 

  1. Tonack S, Aspinal O’Dea M, Jenkins RE, Elliot V, Murray S, Lane CS, Kitteringham NR, Neoptolemos JP, Costello E.  A technically detailed and pragmatic protocol for quantitative serum proteomics using iTRAQ.  Journal of Proteomics 2009; 73(2):352-6.

 

  1. Tonack S, Aspinall-O'Dea M, Neoptolemos JP, Costello E. Pancreatic Cancer: Proteomic Approaches to a Challenging Disease. Pancreatology. 2009 Aug 4;9(5):567-576. 2009 Aug 4;9(5):567-576.. 2009; 9 (5): 567-576.

 

  1. Ghaneh P, Greenhalf W, J Neoptolemos. Factors involved in carcinogenesis and prevention in hepatobiliary cancer. In: Jankowski, Sampliner, Kerr and Fong (Eds). Structure of GI Oncology: A Critical MDT Approach. 2008.

 

  1. Alexakis N, Ghaneh P, Neoptolemos JP.  Epidemiology of pancreatic cancer.  In: Beger HG, Warshaw A, Büchler M, Kozarek R, Lerch M, Neoptolemos JP, Shiratori K, Whitcomb D. (Eds). The Pancreas, Second Edition.  Blackwell Publishing, Massachusetts, USA, 2008, 573-582.

 

  1. Howes, N., Greenhalf, W., and Raraty, G. T. R. Medical Treatment of Chronic Pancreatitis: Antioxidants. In: H.-G. Beger, M. Buchler, R. Kozarek, M. Lerch, J. Neoptolemos, A. Warshaw, D. Whitcomb, and K. Shiratori (eds.), The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, pp. 523-525. Oxford: Blackwell, 2008.

 

  1. Greenhalf, W., Vitone, L. J., and Neoptolemos, J. Familial Pancreatic Cancer. In: H.-G. Beger, M. Buchler, R. Kozarek, M. Lerch, J. Neoptolemos, A. Warshaw, D. Whitcomb, and K. Shiratori (eds.),The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, pp. 591-600. Oxford: Blackwell, 2008.

 

  1. Greenhalf, W., Malats, N., Nilsson, M., Bartsch, D., and Neoptolemos, J. International Registries of Families at High Risk of Pancreatic Cancer. Pancreatology, 8: 558-565, 2008.

 

  1. Carlson, C., Greenhalf, W., and Brentnall, T. A. Screening of Hereditary Pancreatic Cancer Families. In: H.-G. Beger, M. Buchler, R. Kozarek, M. Lerch, J. Neoptolemos, A. Warshaw, D. Whitcomb, and K. Shiratori (eds.), The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery: Blackwell, 2008.

 

  1. Slater, E., Amrillaeva, V., Fendrich, V., Bartsch, D., Earl, J., Vitone, L. J., Neoptolemos, J. P., and Greenhalf, W. Palladin mutation causes familial pancreatic cancer: absence in European families. PLoS Med, 4: e164, 2007.

 

  1. Brand RE, Lerch MM, Rubinstein WS, Neoptolemos JP, Whitcomb DC, Hruban RH, Brentnall TA, Lynch HT, Canto MI, Participants of the Fourth Interantional Symposium of Inherited Diseases of the Pancreas. Recent advances in Clinical Practice.  Advances in counselling and surveillance of patients at risk for pancreatic cancer. Gut, 2007; 56:1460-1469.

 

  1. Grocock, C. J., Vitone, L. J., Harcus, M. J., Neoptolemos, J. P., Raraty, M. G., and Greenhalf, W. Familial pancreatic cancer: a review and latest advances. Adv Med Sci, 52: 37-49, 2007.

 

  1. Vitone, L. J., Greenhalf, W., McFaul, C. D., Ghaneh, P., and Neoptolemos, J. P. The inherited genetics of pancreatic cancer and prospects for secondary screening. Best Pract Res Clin Gastroenterol, 20: 253-83, 2006.

 

  1. Vitone, L. J., Greenhalf, W., Howes, N. R., Raraty, M. G., and Neoptolemos, J. P. Trypsinogen mutations in pancreatic disorders. Endocrinol Metab Clin North Am, 35: 271-87, viii, 2006.

 

  1. McFaul, C., Greenhalf, W., Earl, J., Howes, N., Neoptolemos, J., Kress, R., Sina-Frey, M., Rieder, H., Hahn, S. A., and Bartsch, D. Anticipation in familial pancreatic cancer. Gut, 55: 252-258, 2006.

 

  1. Latchford, A., Greenhalf, W., Vitone, L. J., Neoptolemos, J. P., Lancaster, G. A., and Phillips, R. K. Peutz-Jeghers syndrome and screening for pancreatic cancer. Br J Surg, 93: 1446-55, 2006.

 

  1. Greenhalf, W., and Neoptolemos, J. P. Increasing survival rates of patients with pancreatic cancer by earlier identification. Nat Clin Pract Oncol, 3: 346-7, 2006.

 

  1. Greenhalf, W. An unfavourable prognosis for pancreatic cancer indicates fields of opportunity. Gut, 55: 1533-5, 2006.

 

  1. Earl, J., Yan, L., Vitone, L. J., Risk, J., Kemp, S. J., McFaul, C., Neoptolemos, J. P., Greenhalf, W., Kress, R., Sina-Frey, M., Hahn, S. A., Rieder, H., and Bartsch, D. K. Evaluation of the 4q32-34 locus in European familial pancreatic cancer. Cancer Epidemiol Biomarkers Prev, 15: 1948-55, 2006.

 

  1. Yan, L., McFaul, C., Howes, N., Leslie, J., Lancaster, G., Wong, T., Threadgold, J., Evans, J., Gilmore, I., Smart, H., Lombard, M., Neoptolemos, J., and Greenhalf, W. Molecular analysis to detect pancreatic ductal adenocarcinoma in high-risk groups. Gastroenterology, 128: 2124-30, 2005.

 

  1. Vitone, L. J., Greenhalf, W., Howes, N. R., and Neoptolemos, J. P. Hereditary pancreatitis and secondary screening for early pancreatic cancer. Rocz Akad Med Bialymst, 50: 73-84, 2005.

 

  1. Vitone, L., Greenhalf, W., and Neoptolemos, J. P. Secondary Screening for Pancreatic Cancer in High Risk Groups. In: T. M. Gress, J. P. Neoptolemos, N. R. Lemoine, and F. X. Real (eds.), Exocrine Pancreas Cancer: EPC-RC, pp. 44-61. Hannover: Felsenstein CCCP, 2005.

 

  1. Howes, N., Greenhalf, W., Stocken, D. D., and Neoptolemos, J. P. Cationic trypsinogen mutations and pancreatitis. Clin Lab Med, 25: 39-59, 2005.

 

  1. Hahn, S. A., Vitone, L., Greenhalf, W., Bartsch, D., and Neoptolemos, J. P. Familial Pancreatic Cancer Syndromes. In: T. M. Gress, J. P. Neoptolemos, N. R. Lemoine, and F. X. Real (eds.), Exocrine Pancreas Cancer: EPC-RC, pp. 44-61. Hannover: Felsenstein CCCP, 2005.

 

  1. Greenhalf, W., Vitone, L., and Neoptolemos, J. P. Molecular Diagnosis of Pancreatic Cancer in Pancreatic Juice. In: T. M. Gress, J. P. Neoptolemos, N. R. Lemoine, and F. X. Real (eds.), Exocrine Pancreas Cancer: EPC-RC, pp. 404-425. Hannover: Felsenstein CCCP, 2005.

 

  1. Crnogorac-Jurcevic T, Gangeswaran R, Bhakta V, Capurso G, Lattimore S, Akada M, Sunamura M, Prime W, Campbell F, Brentnall TA, Costello E,Neoptolemos J, Lemoine NR. Proteomic analysis of chronic pancreatitis and pancreatic adenocarcinoma. Gastroenterology 2005; 129(5):1454-63.

 

  1. Cohn, J. A., Neoptolemos, J. P., Feng, J., Yan, J., Jiang, Z., Greenhalf, W., McFaul, C., Mountford, R., and Sommer, S. S. Increased risk of idiopathic chronic pancreatitis in cystic fibrosis carriers. Hum Mutat, 26: 303-7, 2005.

 

  1. Bartsch, D. K., Fendrich, V., Slater, E. P., Sina-Frey, M., Rieder, H., Greenhalf, W., Chaloupka, B., Hahn, S. A., Neoptolemos, J. P., and Kress, R. RNASEL germline variants are associated with pancreatic cancer. Int J Cancer, 117: 718-22, 2005.

 

 

  1. Howes, N., Lerch, M. M., Greenhalf, W., Stocken, D. D., Ellis, I., Simon, P., Truninger, K., Ammann, R., Cavallini, G., Charnley, R. M., Uomo, G., Delhaye, M., Spicak, J., Drumm, B., Jansen, J., Mountford, R., Whitcomb, D. C., and Neoptolemos, J. P. Clinical and genetic characteristics of hereditary pancreatitis in Europe. Clin Gastroenterol Hepatol, 2: 252-61, 2004.

 

  1. Howes, N., Greenhalf, W., Stocken, D. D., and Neoptolemos, J. P. Cationic trypsinogen mutations and pancreatitis. Gastroenterol Clin North Am, 33: 767-87, 2004.

 

  1. Crnogorac-Jurcevic T, Missiaglia E, Blaveri E, Gangeswaran R,Jones M, Terris B, Costello E, Neoptolemos J, Lemoine NR.Molecular alterations in pancreatic carcinoma: expression profiling shows that dysregulated expression S100 genes is highly prevalent. Journal of Pathology 2003;201(1):63-74.

 

  1. Grutzmann, R., McFaul, C., Bartsch, D. K., Sina-Frey, M., Rieder, H., Koch, R., McCarthy, E., Greenhalf, W., Neoptolemos, J. P., Saeger, H. D., and Pilarsky, C. No evidence for germline mutations of the LKB1/STK11 gene in familial pancreatic carcinoma. Cancer Lett, 214: 63-8, 2004.

 

  1. Yan, J., Cohn, J., Neoptolemos, J., Feng, J., Jiang, Z., Greenhalf, W., Ellis, I., and Sommer, S. Increased risk of idiopathic chronic pancreatitis in cystic fibrosis carriers. American Journal of Human Genetics, 73: 1252, 2003.

 

  1. Hahn, S. A., Greenhalf, B., Ellis, I., Sina-Frey, M., Rieder, H., Korte, B., Gerdes, B., Kress, R., Ziegler, A., Raeburn, J. A., Campra, D., Grutzmann, R., Rehder, H., Rothmund, M., Schmiegel, W., Neoptolemos, J. P., and Bartsch, D. K. BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Inst, 95: 214-21, 2003.

 

  1. Weiß FU, Simon P, Witt H, Mayerle J, Hlouschek V, Zimmer KP, Schnekenburger J, Domschke W, Neoptolemos JP, Lerch MM. SPINK1 Mutations, Phenotype Expression and Onset of Diabetes Mellitus in Patients with Trypsinogen Mutation – associated Pancreatitis.  Journal of Medical Genetics 2003; 40(4):e40.

 

  1. Poll, A., Howes, N., Greenhalf, W., Campra, D., Delhaye, M., Elmslie, F., Olah, A., Uomo, G., Neoptolemos, J. P., and Ellis, I. Early age of onset in pancreatic cancer families on the EUROPAC collaborative register. Abstract. Pancreatology, 2002.

 

  1. McFaul, C., Greenhalf, W., Howes, N., Hont, C., Uomo, G., Pasquale, C., Neoptolemos, J., and Ellis, I. Anticipation and earlier male age of onset in familial pancreatic cancer (FPC) patients on the European registry of hereditary pancreatitis and familial pancreatic cancer (EUROPAC). Pancreas, 45: 440, 2002.

 

  1. Threadgold, J., Greenhalf, W., Ellis, I., Howes, N., Lerch, M. M., Simon, P., Jansen, J., Charnley, R., Laugier, R., Frulloni, L., Olah, A., Delhaye, M., Ihse, I., Schaffalitzky de Muckadell, O. B., Andren-Sandberg, A., Imrie, C. W., Martinek, J., Gress, T. M., Mountford, R., Whitcomb, D., and Neoptolemos, J. P. The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease. Gut, 50: 675-81, 2002.

 

  1. Wong, T., Howes, N., Threadgold, J., Smart, H. L., Lombard, M. G., Gilmore, I., Sutton, R., Greenhalf, W., Ellis, I., and Neoptolemos, J. P. Molecular diagnosis of early pancreatic ductal adenocarcinoma in high-risk patients. Pancreatology, 1: 486-509, 2001.

 

  1. Wong, T., Howes, N., Lombard, M., Smart, H., Gilmore, I., Sutton, R., Campbell, F., Kang, Y., Ellis, I., Greenhalf, W., and Neoptolemos, J. Real-time KRAS mutational analysis in the diagnosis of early pancreatic ductal adenocarcinoma. BRITISH JOURNAL OF CANCER, 85: 55-55, 2001.

 

  1. Magee, C. J., Greenhalf, W., Howes, N., Ghaneh, P., and Neoptolemos, J. P. Molecular pathogenesis of pancreatic ductal adenocarcinoma and clinical implications. Surg Oncol, 10: 1-23., 2001.

 

  1. Whitcomb DC, Ulrich CD, Lerch MM, Durie P, Neoptolemos JP, Maisonneurve P, Lowenfels AB.  Conference report: Third International Symposium on Inherited Diseases of the Pancreas.  Pancreatology 2001; 1(5): 423-431.

 

  1. Ellis I and members of the Consensus Committees of the European Registry of Hereditary Pancreatic Diseases, the Midwest Multi-Center Pancreatic Study Group and the International Association of Pancreatology.  Genetic testing for hereditary pancreatitis: Guidelines for indications, counselling, consent and privacy issues. Pancreatology 2001; 1: 401-411.

 

  1. Howes, N., Greenhalf, W., Rutherford, S., O'Donnell, M., Mountford, R., Ellis, I., Whitcomb, D., Imrie, C., Drumm, B., and Neoptolemos, J. P. A new polymorphism for the RI22H mutation in hereditary pancreatitis. Gut, 48: 247-250, 2001.

 

  1. Wong, T., Greenhalf, W., Lombard, M., Smart, H., Gilmore, I., Sutton, R., Fox, J., and Neoptolemos, J. K-ras mutations in the absence of malignancy: Implications for diagnostic and prognostic use. Digestion, 61: 308, 2000.

 

  1. Howes, N., Greenhalf, W., and Neoptolemos, J. Screening for early pancreatic ductal adenocarcinoma in hereditary pancreatitis. Med Clin North Am, 84: 719-38, 2000.

 

  1. Pereira SP, Wilkinson ML, Hodgson SV, Rutherford SN, Neoptolemos JP, Hermon Dowling R. A family with hereditary pancreatitis caused by a mutation in the cationic trypsinogen gene. CME Journal of Gastroenterology 2000; 3: 60-61.

 

  1. Pfützer RH, Barmada MM, Brunskil APJ, Finch R, Hart PS, Neoptolemos J, Furey WF, Witcomb DC.  SPINK1/PSTI Polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis.  Gastroenterology 2000; 119: 615-623.

 

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