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Wednesday 6th July

Time Session  
10:00-12:00 Registration and Welcome Lunch (North Hall)  

11:50-12:00 Welcome to St. Georges Hall (Steve Binns Mbe)  

12:00-14:05 Session One: Signalling Mechanisms, Pancreatic Physiology and Pathophysiology
Chairs: Alexei Tepikin, Miklós Sahin-Tóth, Rolf Graf, Zoltán Rakonczay
12:00-12:20 1S-S1 David Yule Signalling and imaging of pancreatic acinar and stellate cells
12:20-12:30 Oral-1 Eszter Becskeházi Pancreatic ductal fluid- and HCO3- secretion is reduced in aquaporin 1 and 4 knock-out mice

Authors: Eszter Becskeházi, Petra Pallagi, Anita Balázs, Matthias Sendler, Jens Kühn, Zoltán Rakonczay Jr., Péter Hegyi, Viktória Venglovecz
12:30-12:40 Oral-2 Aditi Bhargava F-actin and intracellular calcium modulation by components of the corticotropin-releasing factor (CRF) system in pancreatic acinar cells

Authors: Aditi Bhargava, Burcu Hasdemir
12:40-12:50 Oral-3 Elisabeth Hessmann Context-dependent epigenetic regulation of NFATc1 transcription in pancreatic plasticity

Authors: Elisabeth Hessmann, Nai-ming Chen, Clara Lubeseder-Martellato, Jochen Gaedcke, Jens Siveke, Albrecht Neesse, Volker Ellenrieder
12:50-13:00 Oral-4 Gitta Maria Seleznik Absence of p21 attenuates pancreatic inflammation but does not affect the development of autoimmune pancreatitis

Authors: Gitta Maria Seleznik, Theresia Reding, Lukas Peter, Sabrina Sonda, Mathias Heikenwalder, Rolf Graf
13:00-13:10 Oral-5 Simone Benitz Epigenetic alterations mediated by Ring1b are crucial for acinar-to-ductal metaplasia and pancreatic carcinogenesis

Authors: Simone Benitz, Sabrina Deubler, Jessica Guo, Katja Steiger, Bo Kong, Susanne Raulefs, Christoph W. Michalski, Irene Esposito, Güralp Ceyhan, Jörg Kleeff, Ivonne Regel
13:10-13:20 Oral-6 Ali Aghdassi The lysosomal protease Cathepsin C regulates leukocyte invasion and apoptosis in acute pancreatitis

Authors: Ali Aghdassi, Daniel John, Julia Aschenbach, Matthias Sendler, Ulrich Weiß, Christine Pham, Julia Mayerle, Markus Lerch
13:20-13:30 Oral-7 Isidoro Cobo NR5A2 pancreatic haploinsufficiency cooperates with mutant KRas in the development of aggressive cystic tumors

Authors: Isidoro Cobo, Marta Flandez, Natalia Del Pozo, Julia Melia, Francisco X. Real
13:30-13:40 Oral-8 Tamara Madacsy The impaired function of the plasma membrane Ca2+ pump causes intracellular Ca2+ overload and mitochondrial damage in pancreatic ductal epithelial cells in CFTR knockout mice

Authors: Tamara Madacsy, Julia Fanczal, Petra Pallagi, Viktoria Venglovecz, Zoltan Rakonczay Jr, Peter Hegyi, Jozsef Maleth
13:40-13:50 Oral-9 Daniel Closa Exosomes generated through a pancreas-liver-lung axis are involved in lung damage associated to acute pancreatitis

Authors: Daniel Closa, Vanessa Casas, Montserrat Carrascal, Laia Bonjoch
13:50-14:05 1S-S2 Jason Bruce Protection and response to stress by acinar cells

14:05-15:05 Session Two: State of the Art Symposium: Pancreatic Neuroendocrine Tumours
Chairs: Thomas Gress, Philippe Lévy, Fiona Campbell
14:05-14:20 2S-S1 Paul Komminoth Pathology and prognostic markers of PNETs
14:20-14:35 2S-S2 Sobhan Vinjamuri Nuclear medicine diagnosis and therapy
14:35-14:50 2S-S3 Jens Werner Surgical therapy of sporadic and hereditary PNETs
14:50-15:05 S2-S4 Juan Valle Medical therapies of PNETs

15:05-15:30 Coffee Break  

15:30-16:30 Session Three: Chronic pancreatitis - science
Chairs: David Criddle, Ashok Saluja, Ewa Malecka-Panas, John Windsor
15:30-15:40 Oral-10 Marta Bombardo Inhibition of Class I HDAC ameliorates acute and chronic pancreatitis by reducing leukocyte recruitment, acinar-to-ductal metaplasia and fibrosis.

Authors: Marta Bombardo , Enrica Saponara , Ermanno Malagola , Rong Chen , Rolf Graf , Sabrina Sonda
15:40-15:50 Oral-11 Anne Mößeler Is taurine supplementation useful in case of exocrine pancreatic insufficiency to improve digestibility of fat ?

Authors: Anne Mößeler, Bianca Ahlfänger, Martin Beyerbach, Josef Kamphues
15:50-16:00 Oral-12 Rainer Heuchel Pancreas epithelial-specific knockout of Smad7 in cerulein-induced pancreatic fibrosis

Authors: Rainer Heuchel, Xuan Li, Yasmin Yu, Salvatore Nania, Caroline Verbeke, Matthias Löhr
16:00-16:10 Oral-13 Anita Balázs Imbalance of mucus homeostasis in chronic pancreatitis

Authors: Anita Balázs, Julia Duerr, Zhe Zhou-Suckow, Jolanthe Schatterny, László Tiszlavicz, István B. Németh, Balázs Kui, Zoltán Jr. Rakonczay, Matthias Sendler, Julia Mayer, Jens-Peter Kühn, Marcus A. Mall, Péter Hegyi
16:10-16:20 Oral-14 Constantin Zimmer SNP (rs7877190) as a genetic risk factor for chronic pancreatitis.

Authors: Constantin Zimmer, Sebastian Beer, Mario Krehan, Dóra Mosztbacher, Claudia Ruffert, Joachim Mössner, Patrick Michl , Jonas Rosendahl
16:20-16:30 Oral-15 Jan D'Haese The analgesic effect of the mitochondria targeted antioxidant SkQ in experimental pancreatitis

Authors: Jan D'Haese, Maximilian Weniger, Leonard Reinelt, Jens Neumann, Lesca Holdt, Matthias Ilmer, Bernhard Renz, Werner Hartwig, Jens Werner, Alexandr Bazhin

16:30-18:00 Session Four: Chronic Pancreatitis: Challenges in diagnosis and treatment: IAP/EPC/APA/JPS Guidelines
Chairs: Markus Lerch, Steve Pandol, Chris Halloran, John Windsor
16:30-16:45 4S-S06 Jonas Rosendahl Genetics of chronic pancreatitis
16:45-17:00 4S-S07 Asbjørn Drewes Pathophysiology of pain and medical treatment
17:00-17:15 4S-S08 Thomas Gress Accuracy of EUS for diagnosis of early disease
17:15-17:30 4S-S09 Helmut Friess Surgical treatment of chronic pancreatitis
17:30-17:45 4S-S10 David Whitcomb Clinical classification and Guideline development
17:45-18:00 4S-D Discussion and action points



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Key Dates

Abstract Submission

January 1 - February 22


Abstract Review

March 3 - March 15


Authors informed of abstract acceptance/decline

April 1


Travel Grants Applicant information   

April 7


Organising Committees & Administration