Adopted Trials - Head and neck
Acronym: HOPON
Full Title
Hyperbaric Oxygen for the Prevention of OsteoradioNecrosis. A RCT of hyperbaric oxygen to prevent osteoradionecrosis following at risk surgical procedures on irradiated jaws
Treatment: Other (please specify in Notes)
Phase: 2
Current status: Open to recruitment
Chief Investigator: Mr Richard Shaw
Type of trial: New Technologies
Acronym: ADXS11-001 (Realistic)
Full Title
A Phase I Trial To Assess The Toxicity, Optimum Dose and Scheduling Of Lovaxin-C In Patients Presenting With Human Papilloma Virus Positive (HPV+ve) Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Treatment: Chemotherapy
Phase: 1
Current status: In set-up
Chief Investigator: Mr Terry Jones
Type of trial: Early Phase
Website:
Acronym: IMCAT
Full Title
Immunotherapy for squamous cell carcinoma of the head and neck by Transimmunization. A phase 2a feasibility trial, funded by the NCI-NTRAC and CR-UK.
Treatment: Immunological (immunotherapy & gene therapy)
Phase: 2
Current status: In set-up
Chief Investigator: Mr Terry Jones
Type of trial: Early Phase
Website:
Acronym: REO-018
Full Title
Randomised, double-blind, multicentre 2 stage adaptive phase III study of iv administration of REOLYSIN (Reovirus type 3 dearing) in combination with paclitaxel and carboplatin verus the chemotherapy alone in patients with metastatic or recurrent SCC of the head and neck who have progressed on or after prior platinum-based therapy
Treatment: Immunological (immunotherapy & gene therapy)
Phase: 3
Current status: In set-up
Chief Investigator:
Type of trial: New Technologies
Website:
Acronym: TITAN
Full Title
Trial of Induction TPF in Advanced Head & Neck Cancer
Treatment: Chemotherapy
Phase: 2/3
Current status: In set-up
Chief Investigator: Mr Richard Shaw
Type of trial: Phase 3
Website:
